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CLCNKA Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 14402-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16823024

  • 3313.85 SEK / 150µL
Estimated Shipment: 07-12-2021

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Description

Description

CLC-KA is a kidney-specific chloride channel that mediates transepithelial chloride transport in the thin ascending limb of the Henle loop in the inner medulla. CLC-KA plays a crucial role in urine concentration. The gene encoding human CLC-KA maps to chromosome 1p36. Mutations in this gene may be associated with nephrogenic diabetes insipidus in those cases where mutations in the vasopressin V2 receptor and the AQP2 water channel are lacking. CLC-KB mediates basolateral chloride ion efflux in the thick ascending limb and in more distal nephron segments. The gene encoding human CLC-KB maps to chromosome 1p36. Mutations in this gene cause type III Barter′s syndrome which is characterized by renal salt-wasting and low blood pressure.
Specifications

Specifications

CLCNKA
0.24 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P51800, Q06393, Q9WUB7
chloride channel Ka, ClC K1, CLCK1, CLCNKA, hClC Ka
Rabbit
IgG
150 μL
-20°C
Primary
1187, 12733, 79425
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
CLCNKA
Liquid
Clcnka
CLCNKA Fusion Protein Ag5647
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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