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CLCNKA Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 14402-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
CLC-KA is a kidney-specific chloride channel that mediates transepithelial chloride transport in the thin ascending limb of the Henle loop in the inner medulla. CLC-KA plays a crucial role in urine concentration. The gene encoding human CLC-KA maps to chromosome 1p36. Mutations in this gene may be associated with nephrogenic diabetes insipidus in those cases where mutations in the vasopressin V2 receptor and the AQP2 water channel are lacking. CLC-KB mediates basolateral chloride ion efflux in the thick ascending limb and in more distal nephron segments. The gene encoding human CLC-KB maps to chromosome 1p36. Mutations in this gene cause type III Barter′s syndrome which is characterized by renal salt-wasting and low blood pressure.Specifications
CLCNKA | |
Polyclonal | |
Unconjugated | |
CLCNKA | |
chloride channel Ka, ClC K1, CLCK1, CLCNKA, hClC Ka | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
1187, 12733, 79425 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
0.24 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P51800, Q06393, Q9WUB7 | |
Clcnka | |
CLCNKA Fusion Protein Ag5647 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |