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  7. 16886393

DIDO1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10183-1-AP-20UL

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Product Code. 16886393

  • 1645.54 SEK / 20µL

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Description

Description

The immunogen of this antibody is the C-terminal of isoform 2 of DATF1 (DIDO1).

Dio-1 (Death Inducer-Obliterator-1) is a putative transcription factor that contains two zinc finger motifs. Dio-1 translocates to the nucleus, and activates apoptosis during limb development. Programmed cell death, a highly regulated form of apoptosis, plays an important role in determining the amount of tissue, the shape, and the definition of each digit during limb development. Dio-1 expression is upregulated when an apoptotic signal is detected, and subsequently apoptosis is induced. This process is similar to the expression of NFkB and NGF in response to external signals. Dio-1 expression is suppressed by caspase inhibitors and Bcl-2 expression. This supports the theory that Dio-1 functions in the onset of programmed cell death.
Specifications

Specifications

DIDO1
Polyclonal
Unconjugated
DIDO1
BYE1, C20orf158, DATF 1, DATF1, death inducer obliterator 1, DIDO1, DIDO2, DIDO3, DIO 1, DIO1, hDido1, KIAA0333
Rabbit
Antigen Affinity Chromatography
RUO
11083, 23856, 362286
-20°C
Liquid
Western Blot, Immunofluorescence, Immunocytochemistry, Flow Cytometry
0.3 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q8C9B9, Q9BTC0
Dido1
DIDO1 Fusion Protein Ag0237
20 μL
Primary
Human, Rat, Mouse
Antibody
IgG
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DIDO1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech > 20 μL; Unconjugated

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