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Dynamitin (69-376 AA) Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10030-2-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16826183

  • 1656.73 SEK / 20µL
Estimated Shipment: 03-04-2024
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Description

Description

This antibody is against the internal region (69-376aa) of full length p50 dynamitin.

This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kDa. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.
Specifications

Specifications

Dynamitin (69-376 AA)
Polyclonal
Unconjugated
DCTN2
DCTN 50, DCTN2, DCTN50, dynactin 2, dynactin 2 (p50), Dynactin subunit 2, DYNAMITIN, p50 dynamitin, RBP50
Rabbit
20 μL
Primary
Mouse, Human
Antibody
IgG
Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation
0.13 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q13561, Q99KJ8
Dctn2
Antigen Affinity Chromatography
RUO
10540, 69654
-20°C
Liquid
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