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GAB2 Rabbit, anti-Human, Unconjugated, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 29272-1-AP-20UL
This item is not returnable.
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Description
Growth factor receptor-bound protein 2 (GAB2), an adaptor protein, belongs to the Gab family and is involved in various biologic processes. Gab2 mainly mediates phosphatidylinositol 3-kinase (PI3K) and extracellular signal-regulated kinase (ERK) signaling pathways. Furthermore, Gab2 governs tumorigenic signaling and is a novel potential therapeutic target in leukemia, breast cancer, ovarian cancer, and melanoma. Gab2 is the major 98-kDa phosphoprotein associated with SHP-2, PI 3-kinase, and Grb2 in normal human lymphocytes. (PMID: 32269703, PMID: 28842424, PMID: 28420432, PMID: 10849428)
Specifications
| GAB2 | |
| Polyclonal | |
| Unconjugated | |
| 20 μL | |
| 9846 | |
| Liquid |
| Western Blot, Immunohistochemistry, ELISA | |
| 400 μg/mL | |
| Rabbit | |
| Primary | |
| Human |