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GAB2 Rabbit, anti-Human, Unconjugated, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1656.73 SEK - 4721.67 SEK

Specifications

Antigen GAB2
Concentration 400 μg/mL
Applications Western Blot, Immunohistochemistry, ELISA
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17231446
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Proteintech
29272-1-AP-20UL
20 μL
1656.73 SEK
20µL
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17221446
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Proteintech
29272-1-AP-150UL
150 μL
4721.67 SEK
150µL
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Description

Description

Growth factor receptor-bound protein 2 (GAB2), an adaptor protein, belongs to the Gab family and is involved in various biologic processes. Gab2 mainly mediates phosphatidylinositol 3-kinase (PI3K) and extracellular signal-regulated kinase (ERK) signaling pathways. Furthermore, Gab2 governs tumorigenic signaling and is a novel potential therapeutic target in leukemia, breast cancer, ovarian cancer, and melanoma. Gab2 is the major 98-kDa phosphoprotein associated with SHP-2, PI 3-kinase, and Grb2 in normal human lymphocytes. (PMID: 32269703, PMID: 28842424, PMID: 28420432, PMID: 10849428)

Specifications

Specifications

GAB2
Western Blot, Immunohistochemistry, ELISA
Unconjugated
Rabbit
9846
400 μg/mL
Polyclonal
Liquid
Human
Primary
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Documents

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