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GRAMD4 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 24299-1-AP-20UL
Additional Details : Weight : 0.00010kg
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DescriptionGRAMD4 also termed as Death inducing protein is a 578 amino-acid protein, which contains 1 GRAM domain. GRAMD4 as a multi-pass membrane protein localizes in the Mitochondrion membrane. Overexpression of GRAMD4 results in a strong apoptotic response involving caspase-3 activation and cleavage of poly (ADP-ribose)-polymerase. GRAMD4 is expressed in lung and in primary lung squamous cell carcinoma (LSCC) and shows up-regulation in mitochondria by E2F-1 after addition of 4-hydroxytamoxifen. This evidence suggests that GRAMD4 may be a potential target for cancer therapies.
|dA59H18.1, Death inducing protein, DIP, GRAM domain containing 4, GRAMD4, KIAA0767|
|Antigen Affinity Chromatography|
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|GRAMD4 Fusion Protein Ag19140|