missing translation for 'onlineSavingsMsg'
Learn More

GUK1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10755-1-AP-150UL

Additional Details : Weight : 0.00010kg

 View more versions of this product

Product Code. 16887343

  • 3313.85 SEK / 150µL
Estimated Shipment: 02-12-2021

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Guanylate kinase (GK) catalyzes the ATP-dependent phosphorylation of GMP into GDP. It is essential for recycling GMP and indirectly, cGMP. In prokaryotes (such as Escherichia coli), lower eukaryotes (such as yeast) and in vertebrates, GK is a highly conserved monomeric protein of about 200 amino acids. GK has been shown to be structurally similar to protein A57R (or SalG2R) from various strains of Vaccinia virus. Proteins containing one or more copies of the DHR domain, an SH3 domain as well as a C-terminal GK-like domain, are collectively termed MAGUKs (membrane-associated guanylate kinase homologs) and include Drosophila lethal(1)discs large-1 tumor suppressor protein (gene dlg1); mammalian tight junction protein Zo-1; a family of mammalian synaptic proteins that seem to interact with the cytoplasmic tail of NMDA receptor subunits (SAP90/PSD-95, CHAPSYN-110/PSD-93, SAP97/DLG1 and SAP102); vertebrate 55 kD erythrocyte membrane protein (p55); C. elegans protein lin-2; rat protein CASK; and human proteins DLG2 and DLG3. There is an ATP-binding site (P-loop) in the N-terminal section of GK, which is not conserved in the GK-like domain of the above proteins. However these proteins retain the residues known, in GK, to be involved in the binding of MP.
Specifications

Specifications

GUK1
0.25 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q16774, Q64520
GMK, GMP kinase, Guanylate kinase, guanylate kinase 1, GUK1
Rabbit
IgG
150 μL
-20°C
Primary
14923, 2987, 303179
Immunohistochemistry (Paraffin)
Unconjugated
GUK1
Liquid
Guk1
GUK1 Fusion Protein Ag1205
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Videos
SDS
Documents
Certificates
Special Offers

Special Offers