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STEMCELL Technologies Human Recombinant IL-10

Interleukin 10

2471.14 SEK - 65070.25 SEK

Specifications

Cell Type Dendritic Cells; Hematopoietic Stem and Progenitor Cells; Myeloid Cells; Neurons; T Cells
Purity or Quality Grade ≥95%
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Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17109381
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STEMCELL Technologies
78024.2
1000 μg
65070.25 SEK
1000µg
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Estimated Shipment: 22-04-2024
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17189371
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STEMCELL Technologies
78024
50 μg
7847.00 SEK
50µg
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Estimated Shipment: 04-04-2024
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17199371
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STEMCELL Technologies
78024.1
10 μg
2471.14 SEK
10µg
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Estimated Shipment: 04-04-2024
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Description

Description

  • Interleukin 10 (IL-10) is the founding member of the IL-10 family of class II cytokines
  • All of the IL-10 cytokine family members have a four-helix bundle consisting of α-helical folds
  • Upon binding to its receptor, IL-10 activates signaling through JAK1 and STAT3
  • It is produced by dendritic cells, macrophages, and CD4+ T cells, as well as mast cells, NK cells, neutrophils, and B cells, under specific stimulating conditions (Saraiva & O'Garra)
  • IL-10 can inhibit the expression of pro-inflammatory cytokines and promote healing processes, and is important for the function of regulatory T cells
  • IL-10 also enhances B cell proliferation, immunoglobulin secretion, and class II MHC expression, while IL-10 produced by macrophages inhibits activation of neighboring macrophages, thus allowing a level of self-regulation (Ouyang et al.)
Specifications

Specifications

Dendritic Cells; Hematopoietic Stem and Progenitor Cells; Myeloid Cells; Neurons; T Cells
≥95%
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