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STEMCELL Technologies Human Recombinant IL-10
Interleukin 10
2596.05 SEK - 68359.95 SEK
Specifications
| Cell Type | Dendritic Cells; Hematopoietic Stem and Progenitor Cells; Myeloid Cells; Neurons; T Cells |
|---|---|
| Purity or Quality Grade | ≥95% |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
17109381
|
STEMCELL Technologies
78024.2 |
1000 μg |
68359.95 SEK
1000µg |
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|
17189371
|
STEMCELL Technologies
78024 |
50 μg |
8243.10 SEK
50µg |
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|
17199371
|
STEMCELL Technologies
78024.1 |
10 μg |
2596.05 SEK
10µg |
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Description
- Interleukin 10 (IL-10) is the founding member of the IL-10 family of class II cytokines
- All of the IL-10 cytokine family members have a four-helix bundle consisting of α-helical folds
- Upon binding to its receptor, IL-10 activates signaling through JAK1 and STAT3
- It is produced by dendritic cells, macrophages, and CD4+ T cells, as well as mast cells, NK cells, neutrophils, and B cells, under specific stimulating conditions (Saraiva & O'Garra)
- IL-10 can inhibit the expression of pro-inflammatory cytokines and promote healing processes, and is important for the function of regulatory T cells
- IL-10 also enhances B cell proliferation, immunoglobulin secretion, and class II MHC expression, while IL-10 produced by macrophages inhibits activation of neighboring macrophages, thus allowing a level of self-regulation (Ouyang et al.)
Specifications
| Dendritic Cells; Hematopoietic Stem and Progenitor Cells; Myeloid Cells; Neurons; T Cells | |
| ≥95% |
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Product Title
STEMCELL Technologies Human Recombinant IL-10