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STEMCELL Technologies Human Recombinant IL-10
Interleukin 10
2508.30 SEK - 66048.75 SEK
Specifications
Cell Type | Dendritic Cells; Hematopoietic Stem and Progenitor Cells; Myeloid Cells; Neurons; T Cells |
---|---|
Purity or Quality Grade | ≥95% |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17109381
|
STEMCELL Technologies
78024.2 |
1000 μg |
66048.75 SEK
1000µg |
Estimated Shipment: 04-06-2024 Log in to see stock. |
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17189371
|
STEMCELL Technologies
78024 |
50 μg |
7965.00 SEK
50µg |
Estimated Shipment: 17-05-2024 Log in to see stock. |
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17199371
|
STEMCELL Technologies
78024.1 |
10 μg |
2508.30 SEK
10µg |
Estimated Shipment: 17-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
- Interleukin 10 (IL-10) is the founding member of the IL-10 family of class II cytokines
- All of the IL-10 cytokine family members have a four-helix bundle consisting of α-helical folds
- Upon binding to its receptor, IL-10 activates signaling through JAK1 and STAT3
- It is produced by dendritic cells, macrophages, and CD4+ T cells, as well as mast cells, NK cells, neutrophils, and B cells, under specific stimulating conditions (Saraiva & O'Garra)
- IL-10 can inhibit the expression of pro-inflammatory cytokines and promote healing processes, and is important for the function of regulatory T cells
- IL-10 also enhances B cell proliferation, immunoglobulin secretion, and class II MHC expression, while IL-10 produced by macrophages inhibits activation of neighboring macrophages, thus allowing a level of self-regulation (Ouyang et al.)
Specifications
Dendritic Cells; Hematopoietic Stem and Progenitor Cells; Myeloid Cells; Neurons; T Cells | |
≥95% |