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STEMCELL Technologies Human Recombinant TGF-beta 3
Transforming growth factor beta 3
Brand: STEMCELL Technologies 78131.1
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Description
- Transforming growth factor (TGF) beta 3 is a member of the TGF-β superfamily and regulates diverse cellular phenotypes
- TGF-beta 3 binds to serine-threonine kinase type I and II receptors and activates signal transduction through SMAD2/3 proteins, thus regulating a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, and metabolism (Massagué; McDowell et al.) TGF-beta 3 enhances glycosaminoglycan production by mesenchymal stromal cells, stimulates scar-free healing, and improves glucose tolerance and phenotypic changes in adipocyte morphology (Hall et al.; Holton et al.) TGF-beta 3 induces proliferation of posterofrontal suture-derived mesenchymal stromal cells, and stimulates expression of fibroblast growth factors 2 and 18 (James et al.)
Specifications
| ARVD, FLJ16571, TGFB3, TGF-b3, Transforming growth factor beta-3 | |
| 100 μg | |
| Mesenchymal Cells, PSC-Derived; Mesenchymal Stem and Progenitor Cells | |
| ≥95% |
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Product Title
STEMCELL Technologies Human Recombinant TGF-beta 3
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