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IDO1 Mouse anti-Human, Mouse, Rat, Clone: 3G2G11, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66528-1-IG-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16878485

  • 3313.85 SEK / 150µL
Estimated Shipment: 02-12-2021

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Description

Description

IDO1 is an intracellular heme-containing enzyme that catalyzes the oxidative cleavage of the indole ring of several important regulatory molecules like tryptophan, serotonin, and melatonin. By doing this, IDO1 initiates the production of biologically active metabolites, commonly referred to as kynurenines. IDO1 is widely expressed in a variety of human tissues as well as in macrophages and dendritic cells (DCs). In inflammation, interferons (IFNs) act on specific receptors to trigger IDO1 induction. The production of IFN-gamma and induction of IDO1 represent important antimicrobial mechanisms. Degradation and depletion of tryptophan by IDO1 inhibits the growth of viruses, bacteria and parasites. Furthermore, IDO1 plays a complex and crucial role in immunoregulation during infection, pregcy, autoimmunity, transplantation, and neoplasia.
Specifications

Specifications

IDO1
3G2G11
Unconjugated
IDO1
Liquid
Ido1
IDO1 Fusion Protein Ag3953
Protein G
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Western Blot
1 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P14902, P28776, Q9ERD9
CD107B, IDO, IDO 1, IDO1, INDO, indoleamine 2,3 dioxygenase 1
Mouse
IgG1
150 μL
-20°C
Primary
15930, 3620, 66029
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