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INPP5D Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1656.73 SEK - 4721.67 SEK

Specifications

Antigen INPP5D
Concentration 0.26 mg/mL
Applications Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16899164
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Proteintech
19694-1-AP-20UL
20 μL
1656.73 SEK
20µL
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Estimated Shipment: 23-04-2024
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16889164
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Proteintech
19694-1-AP-150UL
150 μL
4721.67 SEK
150µL
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Estimated Shipment: 23-04-2024
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Description

Description

This antibody is specific to INPP5D.

an SH2-containing inositol phosphatase. A hemopoietic-specific phosphatase that regulates cell survival, growth, cell cycle arrest and apoptosis. Hydrolyzes Ins(1, 3, 4, 5)P4 and PtdIns(3, 4, 5)P3. A cytosolic protein with a SH2 domain in its N-terminus and two NPXY Shc binding motifs at its C-terminus. Upon receptor cross-linking, SHIP is first recruited to the plasma membrane by its SH2, followed by tyrosine phosphorylation on the NPXY motif. Both membrane relocalization and phosphorylation are essential for its regulatory function. Associates with SHC after cytokine stimulation.
Specifications

Specifications

INPP5D
Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation
Unconjugated
Rabbit
Mouse, Rat, Human
P97573, Q92835, Q9ES52
16331, 3635, 54259
Peptide
Primary
-20°C
INPP5D
0.26 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
hp51CN, INPP5D, p150Ship, SHIP, SHIP 1, SHIP1, SIP 145
INPP5D
IgG
Antigen Affinity Chromatography
Antibody
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SDS
Documents

Documents

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