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INPP5D Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 19694-1-AP-150UL

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Product Code. 16889164

  • 4652.90 SEK / 150µL

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Description

Description

This antibody is specific to INPP5D.

an SH2-containing inositol phosphatase. A hemopoietic-specific phosphatase that regulates cell survival, growth, cell cycle arrest and apoptosis. Hydrolyzes Ins(1, 3, 4, 5)P4 and PtdIns(3, 4, 5)P3. A cytosolic protein with a SH2 domain in its N-terminus and two NPXY Shc binding motifs at its C-terminus. Upon receptor cross-linking, SHIP is first recruited to the plasma membrane by its SH2, followed by tyrosine phosphorylation on the NPXY motif. Both membrane relocalization and phosphorylation are essential for its regulatory function. Associates with SHC after cytokine stimulation.
Specifications

Specifications

INPP5D
Polyclonal
Unconjugated
INPP5D
hp51CN, INPP5D, p150Ship, SHIP, SHIP 1, SHIP1, SIP 145
Rabbit
Antigen Affinity Chromatography
RUO
16331, 3635, 54259
-20°C
Liquid
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.26 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P97573, Q92835, Q9ES52
INPP5D
Peptide
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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Product Title
INPP5D Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech > 150 μL; Unconjugated

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