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LRRTM3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1656.73 SEK - 4721.67 SEK
Specifications
Antigen | LRRTM3 |
---|---|
Concentration | 0.4 mg/mL |
Applications | Immunohistochemistry (Paraffin), Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16885315
|
Proteintech
27003-1-AP-20UL |
20 μL |
1656.73 SEK
20µL |
Estimated Shipment: 26-04-2024 Log in to see stock. |
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16875315
|
Proteintech
27003-1-AP-150UL |
150 μL |
4721.67 SEK
150µL |
Estimated Shipment: 26-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Recent evidence suggests that LRRTM3 promotes the processing of amyloid-precursor protein (APP) by the beta-secretase BACE, leading to the proteolytic production of the A-beta42 peptide that is the main component of amyloid plaques. Furthermore, LRRTM3 maps to a region of chromosome 10 linked to both late-onset Alzheimer′s disease (AD) and elevated plasma A-beta42 levels, suggesting that LRRTM3 is a functional and positional candidate gene for AD.Specifications
LRRTM3 | |
Immunohistochemistry (Paraffin), Western Blot | |
Unconjugated | |
Rabbit | |
Human, Mouse, Rat | |
D3ZAL8, Q86VH5, Q8BZ81 | |
216028, 294380, 347731 | |
LRRTM3 Fusion Protein Ag25452 | |
Primary | |
-20°C | |
LRRTM3 |
0.4 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
LRRTM3 | |
LRRTM3 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |