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MCM6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 13347-2-AP-20UL
Additional Details : Weight : 0.00010kg
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DescriptionThe protein encoded by this gene is one of the highly conserved mini-chromosome maintece proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
|MCG40308, MCM6, Mis5, P105MCM|
|Antigen Affinity Chromatography|
|17219, 29685, 4175|
|Immunofluorescence, Immunocytochemistry, Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)|
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|P97311, Q14566, Q62724|
|MCM6 Fusion Protein Ag4180|
|Rat, Mouse, Human|