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MCM7 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 11225-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintece proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme.The protein encoded by this gene is one of the highly conserved mini-chromosome maintece proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.Specifications
MCM7 | |
Polyclonal | |
Unconjugated | |
MCM7 | |
CDABP0042, CDC47, CDC47 homolog, MCM2, MCM7, P1.1 MCM3, P1CDC47, P85MCM, PNAS 146 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
17220, 288532, 4176 | |
-20°C | |
Liquid |
Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry, Flow Cytometry | |
0.27 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
P33993, Q61881 | |
Mcm7 | |
MCM7 Fusion Protein Ag1730 | |
150 μL | |
Primary | |
Rat, Mouse, Human | |
Antibody | |
IgG |