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Melphalan, 94%
Shop All Thermo Scientific Chemicals ProductsDescription
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Melphalan is a phenylalanine derivative of nitrogen mustard with antineoplastic activity with the capacity to alkylate nucleic acids
- Melphalan alkylates DNA at the N-7 position of guanine and induces DNA interstrand cross-linkages, resulting in the inhibition of DNA/RNA synthesis, inducing cytotoxicity against both dividing and non-dividing tumor cells
Applications
- Melphalan has been used in in vitro experiments to treat multiple myeloma in cell lines and breast cancer cell lines
- In in vivo experiments, using rats, it shows a potent therapeutic effect in cases of sarcomatous pulmonary metastases

Specifications
Specifications
Melting Point | 180.0°C |
Infrared Spectrum | Authentic |
Assay Percent Range | 93% min. (HPLC) |
Linear Formula | (ClCH2CH2)2NC6H4CH2CH(NH2)COOH |
Quantity | 5 g |
Formula Weight | 305.2 |
Percent Purity | 94% |
Chemical Name or Material | Melphalan |
Certificates
Certificates
A lot number is required to show results for certificates. To find your lot number on previous orders use our order status area.
Lot Number | Certificate Type | Date | Product Code |
---|---|---|---|
A0460531 | Certificate of Analysis | 27/02/2024 | 458650050,458650010 |
A0428572 | Certificate of Analysis | 03/10/2022 | 458650050,458650010 |
A0427496 | Certificate of Analysis | 02/09/2022 | 458650050,458650010 |
A0422491 | Certificate of Analysis | 30/09/2020 | 458650050,458650010 |
Safety and Handling


- Melphalan
- Danger
- Acute toxicity Category 1
- Acute toxicity Category 2
- Carcinogenicity Category 1B
- Serious eye damage/eye irritation Category 2
- Reproductive toxicity Category 2
- Skin corrosion/irritation Category 2
- H330-Fatal if inhaled.
- H350-May cause cancer.
- H310-Fatal in contact with skin.
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H361-Suspected of damaging fertility or the unborn child.
- H300-Fatal if swallowed.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P302+P352-IF ON SKIN: Wash with plenty of water/.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P362-Take off contaminated clothing.
RUO – Research Use Only
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