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MKP-2 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 1G1C12, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 66349-1-IG-20UL
Additional Details : Weight : 0.00010kg
Description
DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP4 inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus.Specifications
MKP-2 | |
Monoclonal | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q13115, Q62767, Q8BFV3 | |
Dusp4 | |
MKP-2 Fusion Protein Ag1206 | |
20 μL | |
Primary | |
Rat, Human, Mouse, Porcine | |
Antibody | |
IgG1 |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunofluorescence | |
1G1C12 | |
Unconjugated | |
DUSP4 | |
dual specificity phosphatase 4, DUSP4, HVH2, MAP kinase phosphatase 2, MKP 2, MKP2, MKP-2, TYP, VH2 | |
Mouse | |
Protein G | |
RUO | |
100514374, 1846, 319520, 60587 | |
-20°C | |
Liquid |