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MKP-2 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 1G1C12, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66349-1-IG-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16828145

  • 1236.20 SEK / 20µL
Estimated Shipment: 02-12-2021

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Description

Description

DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP4 inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus.
Specifications

Specifications

MKP-2
1G1C12
Unconjugated
DUSP4
Liquid
Dusp4
MKP-2 Fusion Protein Ag1206
Protein G
RUO
Antibody
Monoclonal
Rat, Human, Mouse, Porcine
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunofluorescence
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q13115, Q62767, Q8BFV3
dual specificity phosphatase 4, DUSP4, HVH2, MAP kinase phosphatase 2, MKP 2, MKP2, MKP-2, TYP, VH2
Mouse
IgG1
20 μL
-20°C
Primary
100514374, 1846, 319520, 60587
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