Learn More
NeutraKine IL-17A Mouse anti-Human, Unconjugated, Clone: 1F3E3, Proteintech
Mouse Monoclonal Antibody
1763.23 SEK - 3774.97 SEK
Specifications
Antigen | NeutraKine IL-17A |
---|---|
Clone | 1F3E3 |
Applications | Neutralization, ELISA |
Classification | Monoclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17204656
|
Proteintech
69021-1-IG-25UG |
25 μg |
1763.23 SEK
25µg |
Estimated Shipment: 10-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
17294646
|
Proteintech
69021-1-IG-100UG |
100 μg |
3774.97 SEK
100µg |
Estimated Shipment: 10-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
IL17A, also named as IL-17, is a proinflammatory cytokine. IL-17, synthesized only by memory T cells and natural killer cells, has pleiotropic effects, mainly in the recruitment and activation of neutrophils. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. The IL-17 receptor is a type I transmembrane protein, that is widely expressed on epithelial cells, fibroblasts, B and T cells, and monocytic cells. In psoriatic skin lesions, both Th17 cells and their downstream effector molecules, e.g. IL-17 and IL-22, are highly increased. This antibody is used to Block/Neutralize IL-17A protein.
Specifications
NeutraKine IL-17A | |
Neutralization, ELISA | |
Unconjugated | |
Mouse | |
IgG1 |
1F3E3 | |
Monoclonal | |
Liquid | |
3605 | |
Primary |