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  6. NeutraKine IL-17A Mouse anti-Human, Unconjugated, Clone: 1F3E3, Proteintech

NeutraKine IL-17A Mouse anti-Human, Unconjugated, Clone: 1F3E3, Proteintech

Mouse Monoclonal Antibody

1690.93 SEK - 3620.19 SEK

Specifications

Antigen NeutraKine IL-17A
Clone 1F3E3
Applications Neutralization, ELISA
Classification Monoclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17204656
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Proteintech
69021-1-IG-25UG 		25 ÎĽg
1690.93 SEK
25µg
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17294646
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Proteintech
69021-1-IG-100UG 		100 ÎĽg
3620.19 SEK
100µg
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Description

Description

IL17A, also named as IL-17, is a proinflammatory cytokine. IL-17, synthesized only by memory T cells and natural killer cells, has pleiotropic effects, mainly in the recruitment and activation of neutrophils. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. The IL-17 receptor is a type I transmembrane protein, that is widely expressed on epithelial cells, fibroblasts, B and T cells, and monocytic cells. In psoriatic skin lesions, both Th17 cells and their downstream effector molecules, e.g. IL-17 and IL-22, are highly increased. This antibody is used to Block/Neutralize IL-17A protein.

Specifications

Specifications

NeutraKine IL-17A
Neutralization, ELISA
Unconjugated
Mouse
IgG1
1F3E3
Monoclonal
Liquid
3605
Primary
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NeutraKine IL-17A Mouse anti-Human, Unconjugated, Clone: 1F3E3, Proteintech

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