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NRG1 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 2C6D12, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 66492-1-IG-20UL
Additional Details : Weight : 0.00010kg
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DescriptionThe neuregulins are a family of ErbB/HER ligands encoded by four genes. Neuregulin-1 gene, NRG1, encodes numerous splice variants with differing transcription initiation sites. Neuregulin-1 includes a range of isoforms with varying glycosylation, regulation of expression and function. Neuregulin-1 splice variants each bear an EGF-like domain, though otherwise have unique domain structures, differing functions and discrete tissue distribution. Six types of Neuregulin-1 isoform groups have been defined based on their structural features. Three types are most often described, type I (ARIA, NDF or HRG), type II (GGF) and type III (SMDF). Neuregulin-1 has been linked to schizophrenia and has diverse neural functions. Neuregulin-1 affects cell migration, the differentiation of neural crest and Schwann cells, and acts to upregulate the expression of acetylcholine receptors at muscle fibers during the formation of neuromuscular junctions.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|NRG1 Fusion Protein Ag0803|
|Mouse, Porcine, Rat, Human|
|Western Blot, Immunocytochemistry, Immunofluorescence|
|ARIA, GGF, GGF2, Glial growth factor, Heregulin, HGL, HRG, HRG1, HRGA, NDF, Neu differentiation factor, neuregulin 1, NRG1, Pro NRG1, SMDF|
|102164569, 112400, 211323, 3084|