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NRG1 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 2C6D12, Proteintech

Mouse Monoclonal Antibody

1656.73 SEK - 4721.67 SEK

Specifications

Antigen NRG1
Clone 2C6D12
Concentration 1 mg/mL
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16888415
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Proteintech
66492-1-IG-20UL
20 μL
1656.73 SEK
20µL
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Estimated Shipment: 03-04-2024
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16878415
View Documents Promotion Details
Proteintech
66492-1-IG-150UL
150 μL
4721.67 SEK
150µL
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Estimated Shipment: 03-04-2024
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Description

Description

The neuregulins are a family of ErbB/HER ligands encoded by four genes. Neuregulin-1 gene, NRG1, encodes numerous splice variants with differing transcription initiation sites. Neuregulin-1 includes a range of isoforms with varying glycosylation, regulation of expression and function. Neuregulin-1 splice variants each bear an EGF-like domain, though otherwise have unique domain structures, differing functions and discrete tissue distribution. Six types of Neuregulin-1 isoform groups have been defined based on their structural features. Three types are most often described, type I (ARIA, NDF or HRG), type II (GGF) and type III (SMDF). Neuregulin-1 has been linked to schizophrenia and has diverse neural functions. Neuregulin-1 affects cell migration, the differentiation of neural crest and Schwann cells, and acts to upregulate the expression of acetylcholine receptors at muscle fibers during the formation of neuromuscular junctions.
Specifications

Specifications

NRG1
1 mg/mL
Monoclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
ARIA, GGF, GGF2, Glial growth factor, Heregulin, HGL, HRG, HRG1, HRGA, NDF, Neu differentiation factor, neuregulin 1, NRG1, Pro NRG1, SMDF
NRG1
IgG1
Protein G
Antibody
2C6D12
Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
Mouse
Human, Mouse, Porcine, Rat
P43322, Q02297
102164569, 112400, 211323, 3084
NRG1 Fusion Protein Ag0803
Primary
-20°C
NRG1
Videos
SDS
Documents

Documents

Product Certifications