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Invitrogen™ PARP1 (cleaved Asp214) Recombinant Rabbit Monoclonal Antibody (PARP-H8), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Brand: Invitrogen™ MA537112

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Product Code. 17186698

6810.00 SEK / 200µL

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Description

Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein. Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species.

Specifications

Antigen	PARP1 (cleaved Asp214)
Classification	Recombinant Monoclonal
Concentration	0.5 mg/mL
Formulation	PBS with 0.2% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.	P09874
Gene Symbols	PARP1
Immunogen	A synthetic peptide corresponding to residues surrounding Asp214 of human PARP.
Quantity	200 μL
Primary or Secondary	Primary
Target Species	Human
Product Type	Antibody
Isotype	IgG1 κ

Applications	Flow Cytometry, Western Blot
Clone	PARP-H8
Conjugate	Unconjugated
Gene	PARP1
Gene Alias	5830444G22Rik; ADP-ribosyltransferase (NAD+; ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase 1; ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase NAD(+); Adprp; Adprt; ADPRT 1; ADPRT1; AI893648; ARTD1; C80510; DNA ADP-ribosyltransferase PARP1; msPARP; NAD(+) ADP-ribosyltransferase 1; pADPRT-1; PARP; Parp1; PARP-1; poly (ADP-ribose) polymerase 1; poly (ADP-ribose) polymerase family, member 1; poly (ADP-ribose) polymerase); poly [ADP-ribose] polymerase 1; poly(ADP-ribose) polymerase; poly(ADP-ribose) polymerase 1; poly(ADP-ribose) polymerase PARP-1; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; poly[ADP-ribose] synthase 1; poly[ADP-ribose] synthetase 1; PPOL; Protein poly-ADP-ribosyltransferase PARP1; sPARP-1; synthetase fragment (AA 67); Unknown (protein for IMAGE:8023736); unnamed protein product
Host Species	Rabbit
Purification Method	Protein A/G
Regulatory Status	RUO
Gene ID (Entrez)	142
Content And Storage	-20°C
Form	Liquid

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Invitrogen™ PARP1 (cleaved Asp214) Recombinant Rabbit Monoclonal Antibody (PARP-H8), Invitrogen™ > 200 μL; Unconjugated

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Invitrogen™ PARP1 (cleaved Asp214) Recombinant Rabbit Monoclonal Antibody (PARP-H8), Invitrogen™

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