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PARP1 Mouse anti-Human, Mouse, Rat, Clone: 1D7D4, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66520-1-IG-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16828475

  • 1236.20 SEK / 20µL
Estimated Shipment: 08-12-2021

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Description

Description

This antibody was generated against the N-terminal region of human PARP1 and it recognizes the full-length as well as the cleavage of the PARP1.

Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein. Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species.
Specifications

Specifications

PARP1
1D7D4
Unconjugated
PARP1
Liquid
PARP1
PARP1 Fusion Protein Ag19173
Protein G
RUO
Antibody
Monoclonal
Mouse, Human, Rat
Western Blot, Immunofluorescence, Immunoprecipitation, Immunocytochemistry, Immunohistochemistry (Paraffin)
0.5 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P09874, P11103, P27008
ADPRT, ADPRT 1, ADPRT1, pADPRT 1, PARP, PARP 1, PARP1, poly (ADP ribose) polymerase 1, Poly [ADP ribose] polymerase 1, Poly[ADP ribose] synthase 1, PPOL
Mouse
IgG1
20 μL
-20°C
Primary
11545, 142, 25591
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