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DiscoverX PathHunter™ eXpress GPR171 CHO-K1 β-Arrestin Orphan GPCR Assay
The PathHunter™ eXpress GPR171 CHO-K1 β-Arrestin Orphan GPCR Assay measures GPR171 (GPCR) activity via recruitment of β-Arrestin2. eXpress kits contain all assay materials: cells, reagents, and plates.
Brand: DiscoverX 93-0415E2ACP1L
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Description
The PathHunter™ GPR171 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR171 GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cells overexpress PK-tagged GPR171 and EA-tagged β-Arrestin 2. Activation of GPR171 stimulates the recruitment of β-Arrestin 2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Orphan receptor with unknown ligand.Specifications
| GPCR | |
| 1,000 dp (10 x 96-well) | |
| CHO-K1 |
| Assay-Ready eXpress Kits | |
| GPR171 | |
| GPR171 |
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DiscoverX PathHunter™ eXpress GPR171 CHO-K1 β-Arrestin Orphan GPCR Assay
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