Test
In the LanthaScreen™ Eu Kinase Binding Assay, binding of an Alexa Fluor™ conjugate or tracer such as Kinase Tracer 236 to a kinase is detected by addition of a Eu-labeled anti-tag antibody.
The CRE-bla Jurkat cell line contains a beta-lactamase reporter gene under control of a cAMP response element (CRE) stably integrated into Jurkat cells.
LanthaScreen™ GFP Cellular Assays allow for the analysis of post-translational modifications for a number of target proteins in an live-cell context.
Neurotrophins (NGF, BDNF, NT-3, and NT-4) and their transmembrane receptors (TrkA, TrkB, TrkC, and P75NTR) play important roles in the regulation of neuronal and non-neuronal cell proliferation, differentiation, survival, and death.
The LanthaScreen™ TR-FRET Glucocorticoid Receptor Competitive Binding Assay Kit provides a sensitive and robust method for high-throughput screening (HTS) of ligands for glucocorticoid receptor (GR).
Alexa Fluor™ Kinase Tracer 1710 is detected by addition of a Eu-labeled anti-tag antibody.
GeneBLAzer™ LXR alpha DA (Division Arrested) cells and LXR alpha-UAS-bla HEK 293T 293 cells contain the ligand-binding domain (LBD) of the human Liver-X receptor-alpha(LXR alpha) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™ UAS-bla HEK 293T cell line.
Alexa Fluor™ Kinase Tracer 315 is detected by addition of a Eu-labeled anti-tag antibody.
Jak/Stat signaling pathways play essential roles in the cellular responses to distinct cytokines.
GeneBLAzer™ H2-CRE-bla HEK293T cells contain the human Histamine Receptor 2 (H2) stably integrated into the CellSensor™ CRE-bla HEK293T cell line.
The Tango™ HRH3-bla U2OS DA (Division Arrested) cells contain the human Histamine Receptor H3 (HRH3) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
The GeneBLAzer™ ADRB2-CRE-bla CHO-K1 cells contain the human Adrenergic Beta-2 Receptor (ADRB2), (Accession No. NM_000024.3) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
GeneBLAzer™ GCGR-CRE-bla CHO-K1 Cells contain the human glucagon receptor (GCGR).
The CellSensor™ NFAT-bla Jurkat cell line contains a beta-lactamase reporter gene under control of a Nuclear Factor of Activated T Cells (NFAT) response element stably integrated into Jurkat cells.
GeneBLAzer MCHR2-NFAT-bla CHO-K1 cells contain the human melanin-concentrating hormone receptor 2 (GPR145) stably integrated into the CellSensor NFAT-bla CHO-K1 parental cell line.