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PCP4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 14705-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16823484

  • 1236.20 SEK / 20µL
Estimated Shipment: 07-12-2021

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Description

Description

PCP-4 (Purkinje cell protein 4), also known as PCP4, is a calmodulin (CaM) regulatory protein that is highly expressed in neuronal cells. Through its IQ motif, PCP-4 mediates both the calcium-dependent binding properties of CaM and the rates of association and dissociation of calcium from the C-terminal domain of CaM. The IQ motif contains a serine residue which can be phosphorylated by all isoforms of protein kinase C (PKC). PCP-4 is implicated in uterine leiomyomas, as well as in neurodegenerative disorders such as Alzheimer′s disease and Huntington′s disease. Additionally, overexpression of PCP-4 is thought to play a role in cerebellar hypoplasia, a key feature of Down syndrome.
Specifications

Specifications

PCP4
0.22 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P48539, P63054, P63055
Brain specific antigen PCP 4, PCP4, PEP 19, PEP19, Purkinje cell protein 4
Rabbit
IgG
20 μL
-20°C
Primary
18546, 25510, 5121
Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation
Unconjugated
PCP4
Liquid
PCP4
PCP4 Fusion Protein Ag6388
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse, Rat, Human
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