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PDE8A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1236.20 SEK - 3313.85 SEK

Specifications

Antigen PDE8A
Concentration 0.42 mg/mL
Applications Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin)
Conjugate Unconjugated
Format Liquid
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16822404
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Proteintech
13956-1-AP-150UL
150 μL
3313.85 SEK
150µL
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Estimated Shipment: 31-01-2022
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16832404
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Proteintech
13956-1-AP-20UL
20 μL
1236.20 SEK
20µL
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Estimated Shipment: 31-01-2022
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Description

Description

PDE8A is a Phosphodiesterase (PDEs), which regulate the intracellular levels of cAMP and cGMP. These cyclic nucleotides play an important role as second messengers in multiple physiologic processes, including regulation of vascular resistance, cardiac output, visceral motility, immune response, inflammation, neuroplasticity, vision, and reproduction. PDEs comprise a large superfamily of enzymes divided into 10 families. Different PDEs can be distinguished by their structure, tissue expression, localization, substrate specificity, regulation, and sensitivity to PDE inhibitors. Diversity in structure and specificity of function make PDEs promising targets for the pharmacotherapy of diseases modulated by cyclic nucleotide signaling (MIM 2000).
Specifications

Specifications

PDE8A
Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin)
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Polyclonal
-20°C
0.42 mg/mL
Unconjugated
Rabbit
Human, Rat, Mouse
IgG
Antigen Affinity Chromatography
Antibody
SDS
Product Certifications