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Tocris Bioscience™ PF 06409577
Potent and selective allosteric activator of AMPK
2390.00 SEK - 9335.00 SEK
Specifications
| Chemical Name or Material | PF 06409577 |
|---|---|
| CAS | 1467057-23-3 |
| Synonym | 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic acid |
| Solubility | Soluble to 100mM in DMSO and to 20mM in ethanol |
| Molecular Formula | C19H16ClNO3 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18756559
|
Tocris Bioscience™
6114/50 |
50 mg |
9335.00 SEK
50mg |
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|
18709726
|
Tocris Bioscience™
6114/10 |
10 mg |
2390.00 SEK
10mg |
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Description
Potent and selective allosteric activator of AMPK (EC50 values are 7 and >40000 nM for AMPKα1β1γ1 and AMPKα1β2γ1, respectively). Exhibits minimal off-target effects on a panel of receptors, ion channels, PDEs and kinases. Improves kidney function and reduces proteinuria in a preclinical model of diabetic nephropathy. Orally bioavailable.Specifications
| PF 06409577 | |
| 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic acid | |
| C19H16ClNO3 | |
| Solid | |
| Bioactive Small Molecule |
| 1467057-23-3 | |
| Soluble to 100mM in DMSO and to 20mM in ethanol | |
| 341.79 | |
| Gray | |
| 99% |
Safety and Handling
Recommended Storage : Store at Room Temperature
For Research Use Only.
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Product Title
Tocris Bioscience™ PF 06409577