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PLOD2 Mouse anti-Human, Clone: 1H9E1, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 66342-1-IG-150UL
Additional Details : Weight : 0.00010kg
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DescriptionThe protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|PLOD2 Fusion Protein Ag5779|
|Western Blot, Immunohistochemistry (Paraffin)|
|LH2, Lysyl hydroxylase 2, PLOD2, TLH|