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PTPN11 Mouse anti-Human, Mouse, Rat, Clone: 3F8A8, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66795-1-IG-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16888995

  • 1656.73 SEK / 20µL
Estimated Shipment: 02-04-2024
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Description

Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noo syndrome as well as acute myeloid leukemia.
Specifications

Specifications

PTPN11
Monoclonal
0.8 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P35235, P41499, Q06124
PTPN11
PTPN11 Fusion Protein Ag13649
20 μL
Primary
Mouse, Rat, Human
Antibody
IgG1
Immunohistochemistry (Paraffin), Western Blot
3F8A8
Unconjugated
PTPN11
BPTP3, CFC, NS1, PTP 1D, PTP 2C, PTP2C, PTPN11, SH PTP2, SH PTP3, SHP 2, SHP2, SHPTP2
Mouse
Protein G
RUO
19247, 25622, 5781
-20°C
Liquid
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