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PTPN11 Mouse anti-Human, Mouse, Rat, Clone: 3F8A8, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 66795-1-IG-20UL
Additional Details : Weight : 0.00010kg
Description
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noo syndrome as well as acute myeloid leukemia.Specifications
PTPN11 | |
Monoclonal | |
0.8 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
P35235, P41499, Q06124 | |
PTPN11 | |
PTPN11 Fusion Protein Ag13649 | |
20 μL | |
Primary | |
Human, Rat, Mouse | |
Antibody | |
IgG1 |
Western Blot, Immunohistochemistry (Paraffin) | |
3F8A8 | |
Unconjugated | |
PTPN11 | |
BPTP3, CFC, NS1, PTP 1D, PTP 2C, PTP2C, PTPN11, SH PTP2, SH PTP3, SHP 2, SHP2, SHPTP2 | |
Mouse | |
Protein G | |
RUO | |
19247, 25622, 5781 | |
-20°C | |
Liquid |