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RIP3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1645.54 SEK - 4652.90 SEK

Specifications

Antigen RIP3
Concentration 0.17 mg/mL
Applications Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16897474
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Proteintech
17563-1-AP-20UL
20 ÎĽL
1645.54 SEK
20µL
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16887474
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Proteintech
17563-1-AP-150UL
150 ÎĽL
4652.90 SEK
150µL
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Description

Description

RIP3 is a novel member of RIP Ser/Thr kinase family. It is a potent inducer of apoptosis and is an important component of TNFR1 signaling complex. RIP3 consists of an N-terminal RIP-like-Kinase domain and a unique, non-homologous C-terminus responsible for caspase activation and apoptosis induction. RIP3 is expressed in multiple tissues including hematopoietic cells and plays a functional role in the regulation of apoptosis and NF-kB signaling. It is recruited to the TNFR1 signaling complex in a RIP-dependant manner where it induces apoptosis by activating caspases and/or inhibiting TNFR1-induced NF-kB activation. RIP3 negatively regulates the TLR3-Trif-mediated NF-kB signaling pathway by competing with the binding of Trif to RIP1. The human RIP3 gene is localized in the chromosomal region 14q11.2.
Specifications

Specifications

RIP3
Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
Human, Mouse
Q9QZL0, Q9Y572
11035, 56532
RIP3 Fusion Protein Ag11759
Primary
-20°C
RIPK3
0.17 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Receptor interacting protein 3, RIP 3, RIP like protein kinase 3, RIP3, RIPK3
Ripk3
IgG
Antigen Affinity Chromatography
Antibody
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SDS
Documents

Documents

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RIP3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

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