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RNASE3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 55338-1-AP-150UL

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Product Code. 16886815

  • 4700.76 SEK / 150µL

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Description

Description

ECP (eosinophil cationic protein), also known as RNS3 or RNASE3 (ribonuclease,RNase A family, 3), is a 160 amino acid potent cytotoxic secretory protein that belongs to the pancreatic ribonuclease family. ECP localizes to the granule matrix of the eosinophil and is involved in the immune response system. ECP is a cytotoxin, neurotoxin and helminthotoxin that is secreted by activated human eosinophils. ECP exhibits anti-parasitic, antibacterial and ribonucleolytic activities. It has been suggested that ECP induces the neurotoxic effect known as the Gordon phenomenon, a syndrome manifested by ataxia, muscular rigidity, paralysis and tremor that may lead to death. ECP is considered a marker of eosinophilic inflammation and high levels have been found in cases of active asthma and other allergic diseases.
Specifications

Specifications

RNASE3
Polyclonal
Unconjugated
RNASE3
ECP, Eosinophil cationic protein, Ribonuclease 3, RNase 3, RNASE3, RNS3
Rabbit
Antigen Affinity Chromatography
RUO
53876, 6037
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.32 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O35290, P12724
Ear3, RNASE3
Peptide
150 μL
Primary
Human, Mouse
Antibody
IgG
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RNASE3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech > 150 μL; Unconjugated

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