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RRP8 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1656.73 SEK - 4721.67 SEK

Specifications

Antigen RRP8
Concentration 0.5 mg/mL
Applications Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunofluorescence
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16879624
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Proteintech
20129-1-AP-20UL
20 μL
1656.73 SEK
20µL
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Estimated Shipment: 22-04-2024
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16869624
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Proteintech
20129-1-AP-150UL
150 μL
4721.67 SEK
150µL
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Estimated Shipment: 22-04-2024
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Description

Description

Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at ′Lys-9′ (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.
Specifications

Specifications

RRP8
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunofluorescence
Unconjugated
Rabbit
Rat, Human, Mouse
O43159, Q5U4F0, Q9DB85
101867, 23378, 308911
RRP8 Fusion Protein Ag13994
Primary
-20°C
RRP8
0.5 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Cerebral protein 1, KIAA0409, Nucleomethylin, RRP8
Rrp8
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
Documents

Documents

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