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SMN-Exon7 Mouse anti-Human, Mouse, Clone: 3A8G11, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 60255-1-IG-20UL
This item is not returnable.
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Description
This antibody, 60255-1-Ig, raised against the C-terminal region (275-294 aa) encoded by the exon 7.
The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein - survival motor neuron protein. The SMN complex plays a catalyst role in the assemble of small nuclear ribonucleoproteins, the building blocks of the spliceosome. Mutations in the SMN1 gene are known to cause spinal muscular atrophy 1/2.Specifications
| SMN-Exon7 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P97801, Q16637 | |
| SMN1 | |
| SMN-Exon7 Fusion Protein Ag16615 | |
| 20 μL | |
| Primary | |
| Mouse, Human | |
| Antibody | |
| IgG1 |
| Western Blot, Immunofluorescence, Immunocytochemistry | |
| 3A8G11 | |
| Unconjugated | |
| SMN1 | |
| Component of gems 1, Gemin 1, SMN, SMN1, SMN2, SMNC, SMN-Exon7, SMNT, Survival motor neuron protein, T BCD541 | |
| Mouse | |
| Protein G | |
| RUO | |
| 20595, 6606 | |
| -20°C | |
| Liquid |
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Product Title
SMN-Exon7 Mouse anti-Human, Mouse, Clone: 3A8G11, Proteintech > 20 μL; Unconjugated
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