missing translation for 'onlineSavingsMsg'
SNX6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 10114-1-AP-20UL
Additional Details : Weight : 0.00010kg
VideosSDSDocumentsCertificates Special Offers
DescriptionSNX6 interacts with members of the transforming growth factor-beta family of receptor serine-threonine kinases. These receptors belong to two classes: type II receptors that bind ligand, and type I receptors that are subsequently recruited to transduce the signal. Of the type II receptors, SNX6 was found to interact strongly with ActRIIB and more moderately with wild type and kinase-defective mutants of TbetaRII. Of the type I receptors, SNX6 was found to interact only with inactivated TbetaRI. SNXs 1-4 also interacted with the transforming growth factor-beta receptor family, showing different receptor preferences. Conversely, SNX6 behaved similarly to the other SNX proteins in its interactions with receptor tyrosine kinases. Strong heteromeric interactions were also seen among SNX1, -2, -4, and -6, suggesting the formation in vivo of oligomeric complexes. These findings are the first evidence for the association of the SNX family of molecules with receptor serine-threonine kinases.
|MSTP010, SNX6, sorting nexin 6, TFAF2, TRAF4 associated factor 2|
|Antigen Affinity Chromatography|
|362738, 58533, 72183|
|Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Flow Cytometry|
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|SNX6 Fusion Protein Ag0168|
|Human, Rat, Mouse|