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T-bet Mouse anti-Human, Mouse, Rat, Clone: eBio39D (39D, 3-9D), eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 14-5824-82
Additional Details : Weight : 0.01000kg
Description
T-bet, also known as TBX21, is a T-cell specific transcription factor containing a single T-box DNA-binding domain. It controls the expression of the TH1 cytokine, interferon-gamma. Both Th1 and Th17 cells are crucial in immune regulation and autoimmune disease development. T-bet initiates Th1 lineage development from naive Th precursor cells and directs T cell differentiation to Th1 versus Th17. T-bet is cooperating with Stat4 (signal tranducer and activator of transcription 4) in programming chromatin architecture for Th1 gene expression. Genetic variations in T-bet are associated with susceptibility to aspirin-induced asthma and nasal polyps.Specifications
| T-bet | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 0.09% sodium azide; pH 7.2 | |
| Q9JKD8, Q9UL17 | |
| T-PET, T-bet, TBET, TBLYM, T-box expressed in T cells; T-box protein 21; T-box transcription factor TBX21; T-cell-specific T-box transcription factor T-bet; transcription factor TBLYM | |
| Mouse | |
| Affinity chromatography | |
| RUO | |
| Antibody | |
| Monoclonal | |
| Human, Mouse, Rat |
| ChIP assay, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot | |
| eBio39D (39D, 3-9D) | |
| Unconjugated | |
| TBX21 | |
| Liquid | |
| Tbx21 | |
| IgG1 | |
| 100 μg | |
| 4° C | |
| Primary | |
| 30009, 303496, 57765 |
For Research Use Only.