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TC-S 7009
High affinity and selective HIF-2α inhibitor
1296.94 SEK - 4381.10 SEK
Specifications
| Chemical Name or Material | N-(3-Chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine |
|---|---|
| CAS | 1422955-31-4 |
| Assay Percent Range | >99% |
| Molecular Formula | C12H6ClFN4O3 |
| Formula Weight | Observed MW: 308.65 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18747418
|
Tocris
5243/25 |
25 mg |
4381.10 SEK
25mg |
Estimated Shipment: 05-08-2024 Log in to see stock. |
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|
18771488
|
Tocris
5243/5 |
5 mg |
1296.94 SEK
5mg |
Estimated Shipment: 05-08-2024 Log in to see stock. |
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Description
High affinity and selective HIF-2α inhibitor (Kd = 81 nM). Binds to the HIF-2α PAS-B domain; disrupts HIF-2α-ARNT heterodimerization. Exhibits >60-fold selectivity for HIF-2α over HIF-1α. Decreases HIF-2α DNA-binding and attenuates expression of HIF-2α target genes in vitro.Specifications
| N-(3-Chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine | |
| >99% | |
| Observed MW: 308.65 |
| 1422955-31-4 | |
| C12H6ClFN4O3 |