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TPT1 Mouse anti-Human, Mouse, Rat, Clone: 1G6A10, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66713-1-IG-20UL

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Product Code. 16888845

  • 1645.54 SEK / 20µL

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Description

Description

This antibody detected 22 kDa TPT1 in lysates.

TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium binding proteins. TPT1 is localized in the cytoplasm and widely expressed and serves as a transcriptional activator, calcium transporter, histamine inducer and antiapoptotic caspase 3 inhibitor. TPT1 is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. TPT1 plays a pivotal role in allergic diseases and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer′s disease and Down syndrome.
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TPT1 Mouse anti-Human, Mouse, Rat, Clone: 1G6A10, Proteintech > 20 μL; Unconjugated

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