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TPT1 Mouse anti-Human, Mouse, Rat, Clone: 1G6A10, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 66713-1-IG-20UL
Additional Details : Weight : 0.00010kg
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This antibody detected 22 kDa TPT1 in lysates.TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium binding proteins. TPT1 is localized in the cytoplasm and widely expressed and serves as a transcriptional activator, calcium transporter, histamine inducer and antiapoptotic caspase 3 inhibitor. TPT1 is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. TPT1 plays a pivotal role in allergic diseases and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer′s disease and Down syndrome.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|P13693, P63028, P63029|
|TPT1 Fusion Protein Ag27651|
|Human, Mouse, Rat|
|Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry|
|FLJ27337, Fortilin, Histamine releasing factor, HRF, p02, p23, TCTP, TPT1|
|116646, 22070, 7178|