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TRIB3 Mouse anti-Human, Mouse, Rat, Clone: 2C10C7, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 66702-1-IG-20UL
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Description
A novel inhibitor of cell division, Tribbles, blocks mitosis at a critical point in Drosophila morphogenesis. Recently, mammalian homologues of Tribbles (Trbs) have been identified that control mitogen-activated protein kinase (MAPK) activity. TRIB3 also known as TRB-3, SINK, and SKIP3 is a member of Trbs family. Overexpression of this protein inhibits NF-kB-dependent transcription induced by tumor necrosis factor (TNF) stimulation or its downstream signaling proteins but does not inhibit NF-kB translocation to the nucleus and binding to DNA. TRIB3/SKIP3 is also overexpressed in multiple human tumors and is regulated by hypoxia.Specifications
| TRIB3 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q8K4K2, Q96RU7, Q9WTQ6 | |
| TRIB3 | |
| TRIB3 Fusion Protein Ag25776 | |
| 20 μL | |
| Primary | |
| Human, Rat, Mouse | |
| Antibody | |
| IgG1 |
| Western Blot | |
| 2C10C7 | |
| Unconjugated | |
| TRIB3 | |
| C20orf97, NIPK, SINK, SKIP3, TRB 3, TRB3, TRIB3, Tribbles homolog 3 | |
| Mouse | |
| Protein G | |
| RUO | |
| 228775, 246273, 57761 | |
| -20°C | |
| Liquid |
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Product Title
TRIB3 Mouse anti-Human, Mouse, Rat, Clone: 2C10C7, Proteintech > 20 μL; Unconjugated
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