missing translation for 'onlineSavingsMsg'
Learn More
Learn More
TRX2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 13089-1-AP-20UL
This item is not returnable.
View return policy
Description
Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cystein residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide-isomerase (PDI) and a number of transcription factors such as p53 , NF-kB and AP-1 (T1-151). Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.Specifications
TRX2 | |
Polyclonal | |
Unconjugated | |
TXN2 | |
MT TRX, MTRX, Thioredoxin 2, Thioredoxin, mitochondrial, TRX2, TXN2 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
25828, 56551, 79462 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
0.25 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
P97493, P97615, Q99757 | |
TXN2 | |
TRX2 Fusion Protein Ag3640 | |
20 μL | |
Primary | |
Rat, Mouse, Human | |
Antibody | |
IgG |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
TRX2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech > 20 μL; Unconjugated
Spot an opportunity for improvement?Share a Content Correction