missing translation for 'onlineSavingsMsg'
Learn More

TYMS Mouse anti-Human, Clone: 1F5B7, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66725-1-IG-20UL

 View more versions of this product

Product Code. 16828875

  • 1645.54 SEK / 20µL

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Description

Thymidylate Synthase (TS) (EC 2.1.1.45) converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.
Specifications

Specifications

TYMS
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P04818
TYMS
TYMS Fusion Protein Ag7027
20 μL
Primary
Human
Antibody
IgG1
Western Blot, Immunohistochemistry (Paraffin)
1F5B7
Unconjugated
TYMS
HsT422, Thymidylate synthase, thymidylate synthetase, TMS, TS, TSase, TYMS
Mouse
Protein G
RUO
7298
-20°C
Liquid
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title
TYMS Mouse anti-Human, Clone: 1F5B7, Proteintech > 20 μL; Unconjugated

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.