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ZAP70 Mouse anti-Human, Mouse, Porcine, Clone: 1A11G9, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 60200-1-IG-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16887195

  • 1236.20 SEK / 20µL
Estimated Shipment: 08-12-2021

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Description

Description

Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3′ end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.
Specifications

Specifications

ZAP70
1A11G9
Unconjugated
ZAP70
Liquid
ZAP70
ZAP70 Fusion Protein Ag7943
Protein A
RUO
Antibody
Monoclonal
Human, Porcine, Mouse
Immunohistochemistry (Paraffin), Western Blot
1.37 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P43403, P43404
70 kDa zeta associated protein, SRK, STD, Syk related tyrosine kinase, Tyrosine protein kinase ZAP 70, TZK, ZAP 70, ZAP70
Mouse
IgG2a
20 μL
-20°C
Primary
100739325, 22637, 7535
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