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CH3O(S)(S)O(S)(R)O(S)(R)HO(S)OH(R)CH3O(R)OH(R)CH3OCH3OHOHO(S)O(S)(R)O(S)(R)O(S)(S)CH3OH(R)OH(R)H3CO(R)OH(R)H3CO(R)OH(R)H3COO(S)OH(R)H3COH

CAS RN 18378-89-7

IUPAC Namn: (2S,3S)-3-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-2-{[(2S,4R,5R,6R)-4-{[(2S,4R,5R,6R)-4-{[(2S,4S,5R,6R)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-6-{[(2S,4R,5R,6R)-4-{[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-8,9-dihydroxy-7-methyl-1,2,3,4-tetrahydroanthracen-1-one
Synonymer: Mith antibiotic LA 7017 mitramycin mitramycine MTH mitramycinum plicamycin preparation plicamycin (substance) plicamicina aurlelic acid
Molekylvikt (g/mol): 1085.16
Molekylär sammansättning: C52H76O24
InChi Key: CFCUWKMKBJTWLW-WZIVUMCRSA-N
SMILES: CO[C@@H]([C@@H]1CC2=C(C(=O)[C@H]1O[C@H]1C[C@@H](O[C@H]3C[C@@H](O[C@H]4C[C@](C)(O)[C@H](O)[C@@H](C)O4)[C@H](O)[C@@H](C)O3)[C@H](O)[C@@H](C)O1)C(O)=C1C(O)=C(C)C(O[C@H]3C[C@@H](O[C@H]4C[C@@H](O)[C@H](O)[C@@H](C)O4)[C@H](O)[C@@H](C)O3)=CC1=C2)C(=O)[C@@H](O)[C@@H](C)O
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1

Thermo Scientific Chemicals Mithramycin A, 90 %, från Streptomyces argillaceus

CAS: 18378-89-7 Molekylformel: C52H76O24 Molekylvikt (g/mol): 1085.156 MDL-nummer: MFCD00135618 InChI-nyckel: CFCUWKMKBJTWLW-ZUZMCERRSA-N PubChem CID: 122172942 IUPAC-namn: (2R,3R)-2-[(2R,4S,5S,6S)-4-[(2R,4S,5S,6S)-4-[(2R,4R,5R,6S)-4,5-dihydroxi-4,6-dimetyloxan-2-yl]oxi-5-hydroxi-6-metyloxan-2-yl] oxi-5-hydroxi-6-metyloxan-2-yl]oxi-3-[(lR,3R,4S)-3,4-dihydroxi-l-metoxi-2-oxopentyl]-6-[(2S,4S,5S,6S)-4-[(2S,4S,5R,6S)-4,5-dih LEDER: CC1C(C(CC(O1)OC2CC(OC(C2O)C)OC3=CC4=CC5=C(C(=O)C(C(C5)C(C(=O)C(C(C)O)O)OC)OC6CC(C(C(O6)C)O)OC7CC(C(C(O7)C)O)OC8CC(C(C(O8)C)O)(C)O)C(=C4C(=C3C)O)O)O)O

Molekylformel C52H76O24
PubChem CID 122172942
MDL-nummer MFCD00135618
IUPAC-namn (2R,3R)-2-[(2R,4S,5S,6S)-4-[(2R,4S,5S,6S)-4-[(2R,4R,5R,6S)-4,5-dihydroxi-4,6-dimetyloxan-2-yl]oxi-5-hydroxi-6-metyloxan-2-yl] oxi-5-hydroxi-6-metyloxan-2-yl]oxi-3-[(lR,3R,4S)-3,4-dihydroxi-l-metoxi-2-oxopentyl]-6-[(2S,4S,5S,6S)-4-[(2S,4S,5R,6S)-4,5-dih
CAS 18378-89-7
InChI-nyckel CFCUWKMKBJTWLW-ZUZMCERRSA-N
LEDER CC1C(C(CC(O1)OC2CC(OC(C2O)C)OC3=CC4=CC5=C(C(=O)C(C(C5)C(C(=O)C(C(C)O)O)OC)OC6CC(C(C(O6)C)O)OC7CC(C(C(O7)C)O)OC8CC(C(C(O8)C)O)(C)O)C(=C4C(=C3C)O)O)O)O
Molekylvikt (g/mol) 1085.156
2

Mithramycin A, TRC

CAS: 18378-89-7 Molekylformel: C52H76O24 Molekylvikt (g/mol): 1085.15 Synonym: [1S(2S,3S)]-5-Deoxy-1-C-[7-[[2,6-dideoxy-3-O-(2,6-dideoxy-β-D-arabino-hexopyranosyl)-β-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-β-D-ribo-hexopyranosyl-(1→3)-O-2,6-dideoxy-β-D-arabino-hexopyranosyl-(1→3)-2,6-dideoxy-β-D-lyxo-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-D-threo-2-pentulose,Mithramycin,A 2371,Antibiotic LA 7017,Aureolic Acid,Mithracin,Mitramycin,NSC 24559,PA 144,Plicamycin,Plicatomycin LEDER: CC(=O)NCCc1c2c(ccc(O[C@H]3C(OC(C)=O)C(OC(C)=O)[C@@H](OC(C)=O)C(C(=O)OC)O3)c2)n(C(=O)OC(C)(C)C)c1

Molekylformel C52H76O24
CAS 18378-89-7
LEDER CC(=O)NCCc1c2c(ccc(O[C@H]3C(OC(C)=O)C(OC(C)=O)[C@@H](OC(C)=O)C(C(=O)OC)O3)c2)n(C(=O)OC(C)(C)C)c1
Molekylvikt (g/mol) 1085.15
Synonym [1S(2S,3S)]-5-Deoxy-1-C-[7-[[2,6-dideoxy-3-O-(2,6-dideoxy-β-D-arabino-hexopyranosyl)-β-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-β-D-ribo-hexopyranosyl-(1→3)-O-2,6-dideoxy-β-D-arabino-hexopyranosyl-(1→3)-2,6-dideoxy-β-D-lyxo-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-D-threo-2-pentulose,Mithramycin,A 2371,Antibiotic LA 7017,Aureolic Acid,Mithracin,Mitramycin,NSC 24559,PA 144,Plicamycin,Plicatomycin
3

Melford Plicamycin

Plicamycin, även känd som mithramycin eller Mithracin, är ett antineoplastiskt antibiotikum som produceras av bakterien Streptomyces plicatus.

Molekylformel C52H76O24
CAS 18378-89-7
Kemiskt namn eller material Plicamycin
4

Tocris Bioscience™ Mithramycin A
GREENER_CHOICE

5

Plicamycin, MedChemExpress

MedChemExpress Plicamycin is a selective specificity protein 1 (Sp1) inhibitor. Plicamycin inhibits the growth of various cancers by decreasing Sp1 protein.

ENCOMPASS_PREFERRED
Molekylformel C52H76O24
Rekommenderad förvaring Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Formel vikt 1085.15
Hållbarhet Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Hälsofara 1 H302
Löslighetsinformation DMSO : ≥ 100 mg/mL (92.15 mM)
Anteckningar om renhetsgrad Research
Fysisk form Solid
Kvalitet Research
Färg Yellow
CAS 18378-89-7
LEDER O=C([C@H]([C@@]([C@H](OC)C([C@@H](O)[C@H](O)C)=O)([H])C1)O[C@@](O[C@H](C)[C@H]2O)([H])C[C@H]2O[C@@](O[C@H](C)[C@@H]3O)([H])C[C@H]3O[C@@](O[C@H](C)[C@H]4O)([H])C[C@@]4(O)C)C(C1=CC5=CC(O[C@H](O[C@H](C)[C@H]6O)C[C@H]6O[C@@](O[C@H](C)[C@H]7O)([H])C[C@H]7O)=C(C)C(O)=C85)=C8O
Molekylvikt (g/mol) 1085.15
Synonym Mithramycin A
Kemiskt namn eller material Plicamycin
Procent renhet 98.0%
För användning med (applikation) Cancer-programmed cell death