CAS RN 839707-37-8

IUPAC Namn: N-(3-{7-[(1,3-dimethyl-1H-pyrazol-5-yl)amino]-1-methyl-2-oxo-1H,2H,3H,4H-[1,3]diazino[4,5-d]pyrimidin-3-yl}-4-methylphenyl)-3-(trifluoromethyl)benzamide

Synonymer: N-(3-{7-[(2,5-dimethylpyrazol-3-yl)amino]-1-methyl-2-oxo-4H-[1,3]diazino[4,5-d]pyrimidin-3-yl}-4-methylphenyl)-3-(trifluoromethyl)benzamide

Molekylvikt (g/mol): 550.55

Molekylär sammansättning: C27H25F3N8O2

InChi Key: NBZFRTJWEIHFPF-UHFFFAOYSA-N

SMILES: CN1N=C(C)C=C1NC1=NC=C2CN(C(=O)N(C)C2=N1)C1=C(C)C=CC(NC(=O)C2=CC(=CC=C2)C(F)(F)F)=C1

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Pluripotin, MedChemExpress

MedChemExpress Pluripotin is a dual inhibitor of ERK1 and RasGAP with KDs of 98 nM and 212 nM, respectively. Pluripotin also inhibits RSK1, RSK2, RSK3, and RSK4 with IC50s of 0.5, 2.5, 3.3, and 10.0 μM, respectively.

Prissättning och tillgänglighet
Specifikationer

Molekylformel	C₂₇H₂₅F₃N₈O₂
Rekommenderad förvaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formel vikt	550.54
Hållbarhet	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Löslighetsinformation	DMSO : ≥ 33 mg/mL (59.94 mM)
Anteckningar om renhetsgrad	Research
Fysisk form	Solid
Kvalitet	Research
Färg	White
CAS	839707-37-8
LEDER	CN1C(NC2=NC=C3C(N(C)C(N(C4=CC(NC(C5=CC=CC(C(F)(F)F)=C5)=O)=CC=C4C)C3)=O)=N2)=CC(C)=N1
Molekylvikt (g/mol)	550.54
Synonym	SC1
Kemiskt namn eller material	Pluripotin
Procent renhet	98.19%
För användning med (applikation)	Cancer-Kinase/protease

STEMCELL Technologies Pluripotin

PI3K and MEK/ERK pathway inhibitor; Inhibits RasGAP and ERK1

Prissättning och tillgänglighet
Specifikationer

Molekylformel	C₂₇H₂₅F₃N₈O₂
CAS	839707-37-8
Synonym	SC-1
Renhet	≥98%

CAS RN 839707-37-8

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