CAS RN 915363-56-3
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Tocris Bioscience™ KIN001-266
Potent and selective Tpl2 (MAP3K8) inhibitor
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Cot inhibitor-2, MedChemExpress
MedChemExpress Cot inhibitor-2 is a potent, selective and orally active cot (Tpl2/MAP3K8) inhibitor with an IC50 of 1.6 nM. Cot inhibitor-2 inhibts TNF-α production in LPS-stimulated human whole blood with an IC50 of 0.3 μM.