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4EBP1 Mouse anti-Human, Mouse, Rat, Clone: 2C3F3, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 60246-1-IG-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16827285

  • 1236.20 SEK / 20µL
Estimated Shipment: 02-12-2021

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Description

Description

The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport, and membrane trafficking events including endocytosis and transcytosis. KIF1C is a member of the KIF1/Unc104 family of kinesin-like proteins, which are involved in the transport of mitochondria or synaptic vesicles in axons. Human KIF1C maps to chromosome 17p13 and encodes a predicted 1,103 amino acid protein with abundant expression in heart and skeletal muscle. Tyrosine phosphorylation is a putative regulator of KIF1C mediated retrograde transport of Golgi vesicles to the endoplasmic reticulum. KIF1C is capable of forming homodimers and can noncovalently associate with 14-3-3 beta, gamma, epsilon and zeta. In mouse macrophages, KIF1C is required for anthrax lethal toxin resistance.
Specifications

Specifications

4EBP1
2C3F3
Unconjugated
EIF4EBP1
Liquid
EIF4EBP1
4EBP1 Fusion Protein Ag18985
Protein A
RUO
Antibody
Monoclonal
Mouse, Human, Rat
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunofluorescence
1.6 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q13541, Q60876, Q62622
4E BP1, 4EBP1, BP 1, eIF4E binding protein 1, EIF4EBP1, PHAS I
Mouse
IgG2b
20 μL
-20°C
Primary
116636, 13685, 1978
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