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Invitrogen™ Human ESRRA, Ligand Binding Domain, GST Tag Recombinant Protein Product Code.: 10592215
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Invitrogen™ Human ESRRA, Ligand Binding Domain, GST Tag Recombinant Protein

Product Code. 10592215
50 μg, Each
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Quantity:
50 μg
Unit Size:
Each
This item is not returnable. View return policy

For Research Use Only. All usage must comply with product instructions.

Product Code. 10592215

Brand: Invitrogen™ PV4665

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This item is not returnable. View return policy

For Research Use Only. All usage must comply with product instructions.

Description

Recombinant Protein

ESRRA (estrogen-related receptor alpha) ligand binding domain is a 54.35 kDa recombinant human protein (amino acids 180-423) expressed as a GST fusion protein in baculovirus-infected insect cells. ERR alpha was expressed and purified in the absence of exogenous ligands, making it ideal for ligand binding and coregulator displacement studies. Protein Form: Recombinant, Ligand Binding Domain

Estrogen-related receptor alpha 1 (ERR alpha, ERR1) is an orphan member of the nuclear hormone receptor superfamily. All the ERR family members share an almost identical DNA-binding domain, which has 68% amino acid identity with that of estrogen receptor. This protein binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-tnaaggtca-3' can bind to the medium-chain acyl coenzyme a dehydrogenase (mcad) response element nrre-1 and may act as an important regulator of mcad promoter. Studies have shown that ERR1 functions a metabolic regulator and is often expressed in tissues that preferentially metabolize fatty acids. The corresponding gene for the ERR1 is NR3B1.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P11474
Concentration See Label
For Use With (Application) Ligand Binding Assay
Formulation proprietary buffer with no preservative
Gene ID (Entrez) 2101
Name Human ESRRA, Ligand Binding Domain, GST Tag
Quantity 50 μg
Regulatory Status RUO - research use only
Gene Alias ERR alpha; ERR1; ERRa; ERRalpha; ERR-alpha; Errra; ESRL1; ESRRA; ESRRA1; ESRRA2; estrogen receptor related 1; estrogen receptor-like 1; estrogen related receptor alpha; estrogen related receptor alpha 1; estrogen related receptor, alpha; estrogen-related nuclear receptor alpha; estrogen-related receptor alpha; estrogen-related receptor, alpha; Estrra; HERR1; LOW QUALITY PROTEIN: steroid hormone receptor ERR1; NR3B1; Nuclear receptor subfamily 3 group B member 1; orphan nuclear receptor; steroid hormone receptor ERR1; Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR-alpha) (Estrogen receptor-like 1)
Common Name ESRRA
Protein Length 180-423
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Expression System Baculovirus
Form Liquid
Protein Subtype Hormone Receptors
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Lot Number Certificate Type Date Product Code
Lot Number2077928B Certificate TypeCertificate of Analysis Date10/03/2020 Product CodePV4665
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