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Invitrogen™ Human PIK3CD/PIK3R1 (p110 delta/p85 alpha), His Tag Recombinant Protein Product Code.: 15449063

Invitrogen™ Human PIK3CD/PIK3R1 (p110 delta/p85 alpha), His Tag Recombinant Protein

Product Code. 15449063
100 μg, 100µg
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Quantity:
1 mg
100 μg
20 μg
Unit Size:
100µg
1mg
20µg
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Product Code. 15449063

Brand: Invitrogen™ PV6452

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This item is not returnable. View return policy

Recombinant Protein

Phosphatidylinositol 3-kinase (PI3K) is composed of a catalytic subunit (p110-delta) and a regulatory subunit (p85-alpha in this case), which are encoded by the PIK3CD and PIK3R1 genes. PI3K phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It plays a role in oncogenic transformation and is consistently expressed at a high level in AML blast cells. PI3K can play a selective role in the amplification of phosphatidylinositol (3,4,5) trisphosphate (PIP3) levels that leads to neutrophil polarization, and regulates directional migration, but not random locomotion. The PI3K signaling pathway is involved in immune responses relevant to the pathogenesis of rheumatoid arthritis and other inflammatory diseases.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O00329, P27986
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50 mM sodium phosphate with 0.1 mM PMSF, 0.25 mM DTT, 150 mM Imidazole, 25% glycerol, 300 mM NaCl and no preservative; pH 7
Gene ID (Entrez) 5293, 5295
Molecular Weight (g/mol) 84.7-120.6 kDa
Name Human PIK3CD/PIK3R1 (p110 delta/p85 alpha), His Tag
Quantity 100 μg
Gene Alias PIK3CD; PIK3R1
Common Name PIK3CD/PIK3R1
Gene Symbol PIK3R1/PIK3CD
KinaseFamily PI3 Kinase Family
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-tag
Sequence Full length
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Expression System Insect cells
Form Liquid
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