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Invitrogen™ PIK3CD/PIK3R1 (p110 delta/p85 alpha) Recombinant Human Protein, His tag

Phosphatidylinositol 3-kinase (PI3K) is composed of a catalytic subunit (p110δ) and a regulatory subunit (p85α in this case), which are encoded by the PIK3CD and PIK3R1 genes. PI3K phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring.

Brand:  Invitrogen™ PV6452

Additional Details : Weight : 0.01000kg

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Product Code. 15449063

  • 12490.00 SEK / 100µg


Estimated Shipment date
from Supplier 02-10-2018
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Description

Description

Phosphatidylinositol 3-kinase (PI3K) plays a role in oncogenic transformation and is consistently expressed at a high level in AML blast cells. PI3K can play a selective role in the amplification of phosphatidylinositol (3,4,5) trisphosphate (PIP3) levels that leads to neutrophil polarization, and regulates directional migration, but not random locomotion. The PI3K signaling pathway is involved in immune responses relevant to the pathogenesis of rheumatoid arthritis and other inflammatory diseases.

  • Available in 3 convenient sizes
  • Validated in our Adapta™ and Kinase Binding assays
  • A full length protein that can help advance your research when used with validated assays
Specifications

Specifications

NP_852664.1|NP_005017.3
50mM sodium phosphate (pH 7.0), 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, and 25% glycerol.
120.6kDa|84.7kDa
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
p110 delta/p85 alpha|regulatory subunit 1 (alpha)|p110δ/p85α|phosphoinositide-3-kinase
Kinase Assay
PI3 Kinase Family
Yes
Target & Lead Identification & Validation|Kinase Biology|Biochemical Kinase Assays|Industrial & Applied Science|Pharma & Biopharma
5295, 5293
100μg
Full Length
PIK3R1|PIK3CD
Baculovirus
Human
His Tag
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