CAS RN 485-49-4
CAS RN 485-49-4
IUPAC Name:
(10R)-10-[(5S)-6-methyl-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3,5,11-trioxatricyclo[7.3.0.0²,⁶]dodeca-1,6,8-trien-12-one
Synonyms:
bicuculline d-bicuculline bicculine bicucullin
Molecular Weight (g/mol):
367.36
Molecular Formula:
C20H17NO6
InChi Key:
IYGYMKDQCDOMRE-ZWKOTPCHSA-N
SMILES:
CN1CCC2=CC3=C(OCO3)C=C2[C@H]1[C@@H]1OC(=O)C2=C3OCOC3=CC=C12
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Medchem Express Bicuculline, MedChemExpress
MedChemExpress Bicuculline ((+)-Bicuculline; d-Bicuculline), as a convulsant alkaloid, is a competitive neurotransmitter GABAA receptor antagonist (IC50=2 μM). Bicuculline also blocks Ca2+-activated potassium (SK) channels and subsequently blocks the slow afterhyperpolarization (slow AHP) .
