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1 – 15 av 1,453 Resultat
1

Tocris Bioscience™ Urolithin A
GREENER_CHOICE

PI 3-K/Akt/mTOR signaling pathway inhibitor; blocks phosphorylation of Akt and p70S6K in pancreatic ductal adenocarcinoma (PDAC)

Molekylformel C13H8O4
Rekommenderad förvaring Store at -20°C
Formel vikt 228.2
CAS 1143-70-0
Kemiskt namn eller material 3,8-Dihydroxy-6H-dibenzo[b,d]pyran-6-one
Renhet 98%
2

Tocris Bioscience™ DMSO, sterile filtered
GREENER_CHOICE

Solvent for polar and nonpolar compounds

3

Tocris Bioscience™ Vemurafenib
GREENER_CHOICE

Potent BRAF and CRAF inhibitor

Molekylformel C23H18ClF2N3O3S
Rekommenderad förvaring Store at -20°C
CAS 918504-65-1
Mål Raf Kinase Inhibitors
Kemiskt namn eller material N-[3-[[5-(4-Chlorophenyl)-1 H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide
Renhet 0.98
4

Tocris Bioscience™ Mirabegron
GREENER_CHOICE

Potent and selective β3 agonist

Molekylformel C21H24N4O2S
CAS 223673-61-8
Kemiskt namn eller material 2-Amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide
Renhet 98%
5

Tocris Bioscience™ Auxinole
GREENER_CHOICE

Auxin antagonist of TIR1/AFB receptors; also OsTIR1 inhibitor in auxin-inducible degron (AID) system

Molekylformel C20H19NO3
Rekommenderad förvaring Store at -20°C
CAS 86445-22-9
Mål Molecular Glues
Kemiskt namn eller material α-[2-(2,4-Dimethylphenyl)-2-oxoethyl]-1H-indole-3-acetic acid
Renhet 98%
6

Tocris Bioscience™ DMG-PEG 2000
GREENER_CHOICE

PEGylated myristoyl diglyceride; commonly used in the formation of lipid nanoparticles (LNPs)

7

Tocris Bioscience™ Conivaptan Hydrochloride
GREENER_CHOICE

Very high affinity vasopressin V1A and V2 antagonist; orally bioavailable

Molekylformel C32H26N4O2.HCl
Rekommenderad förvaring Desiccate at Room Temperature
Formel vikt 535.04
CAS 168626-94-6
Kemiskt namn eller material N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][benzazepin-6(1H)-yl)carbonyl]phenyl-[1,1'-biphenyl]-2-carboxamide hydrochloride
Renhet 98%
8

Tocris Bioscience™ Click N-Acetylmuramic acid - azide
GREENER_CHOICE

Bacterial peptidoglycan derivative; suitable for 'click'-conjugation to fluorescent dyes

9

Tocris Bioscience™ GSK 2193874
GREENER_CHOICE

Potent and selective TRPV4 antagonist; orally active

Molekylformel C37H38BrF3N4O
Rekommenderad förvaring Store at 4°C
Formel vikt Observed MW: 691.62
CAS 1336960-13-4
Kemiskt namn eller material 3-([1,4'-Bipiperidin]-1'-ylmethyl)-7-bromo-N-(1-phenylcyclopropyl)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxamide
Analysprocentintervall >98%
10

Tocris Bioscience™ TSA Vivid Fluorophore kit 520
GREENER_CHOICE

Signal amplification kit for use in ISH, ICC and IHC

11

Tocris Bioscience™ SB 431542
GREENER_CHOICE

Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7

Molekylformel C22H16N4O3
Rekommenderad förvaring Store at Room Temperature
Formel vikt 384.39
CAS 301836-41-9
12

Tocris Bioscience™ L-Azidohomoalanine hydrochloride
GREENER_CHOICE

Unnatural Amino Acids

13

Tocris Bioscience™ Thalidomide-Cyanine 5
GREENER_CHOICE

High affinity cereblon fluorescent probe

14

Tocris Bioscience™ NBD-PE
GREENER_CHOICE

Fluorescent label for lysosomal lipid bodies

15

Tocris Bioscience™ Dooku 1
GREENER_CHOICE

Reversibly blocks Yoda1 activity; does not affect constitutive Piezo1 activity

Molekylformel C13H9Cl2N3OS
Rekommenderad förvaring Store at 4°C
Formel vikt 326.2
CAS 2253744-54-4
Mål Other Piezo Channel Compounds
Kemiskt namn eller material 2-[(2,6-Dichlorobenzyl)thio)-5-(1 H-pyrrol-2-yl)-1,3,4-oxadiazole
Renhet 98%