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Bicuculline, MedChemExpress

MedChemExpress Bicuculline ((+)-Bicuculline; d-Bicuculline), as a convulsant alkaloid, is a competitive neurotransmitter GABAA receptor antagonist (IC50=2 μM). Bicuculline also blocks Ca2+-activated potassium (SK) channels and subsequently blocks the slow afterhyperpolarization (slow AHP) .

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Specifikationer

Molekylformel	C₂₀H₁₇NO₆
Rekommenderad förvaring	4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Formel vikt	367.35
Hållbarhet	4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Hälsofara 1	H300∣H311+H331∣H400
Löslighetsinformation	DMSO : 50 mg/mL (136.11 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
Anteckningar om renhetsgrad	Research
Fysisk form	Solid
Kvalitet	Research
Färg	White
CAS	485-49-4
LEDER	O=C1O[C@@H]([C@H]2N(C)CCC3=C2C=C(OCO4)C4=C3)C5=CC=C(OCO6)C6=C51
Molekylvikt (g/mol)	367.35
Synonym	(+)-Bicuculline d-Bicuculline
Kemiskt namn eller material	Bicuculline
Procent renhet	98.0%

CAS RN 485-49-4

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